SELF-DEGRADABLE TRANSDERMAL THERAPEUTIC SYSTEM WITH IMPROVED FUNCTIONAL PARAMETERS AND EFFICACY Russian patent published in 2014 - IPC A61K9/70 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and represents a self-degradable transdermal therapeutic system (TTS) containing at least one active ingredient, at least one agent disabling the active substance with the agent representing a solid substance or a paste, at least one release agent between the active substance and the agent disabling the active substance; the release agent represents a liquid-permeable and solid-impermeable layer, a mobile phase and at least one mechanical agent for perforating at least one adjacent layer of the TTS; the perforation agent has a dull outline and an acute or pointed area inside; when the TTS is released after the use, the perforation agent degrades the release agent between the release agent and the agent disabling the active ingredient thereby it enables the mobile phase supplied onto the agent disabling the active ingredient and enabling the contact of the active ingredient with the agent disabling the active ingredient, while the active ingredient is degraded by this contact.

EFFECT: device enables reducing a risk of undesired release of the preparation in transportation, provides the prolonged storage.

12 cl