METHOD FOR HYPOCALCEMIA CORRECTION IN CHILDREN UNDER AGE OF TWO YEARS OLD SUFFERING CONVULSIVE DISORDER Russian patent published in 2014 - IPC A61K31/592 A61K33/06 G01N33/84 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly to paediatrics. If ionised blood serum calcium is less than 0.9 mmole/l and the relation of ionised Ca/inorganic phosphorus is 0.3 or more, calcium gluconate 1.0 ml is introduced intramuscularly 7-10 times/day in a combination with the oral administration of 10% calcium chloride 5.0 ml 7-10 times/day and 0.5% alcohol solution of vitamin D₂ 8000 IU a day. If observing comorbid hypomagnesaemia (Mg below 0.66 mmole/l), 25% magnesium sulphate 1 ml is introduced intramuscularly once a day. If the calcium level is less than 0.9 mmole/l and the relation of ionised Ca/inorganic phosphorus is less than 0.3 instead of vitamin D₂0, Parathyreoidin 25-0.5 ml is administered intramuscularly 3 times a day. If ionised calcium is more than 1.1 mmole/l and magnesium is more than 0.66 mmole/l, 10% calcium chloride 5.0 ml is orally administered 7-10 times a day, and vitamin D₂ 8000 IU a day or substituting Parathyreoidin in a dose of 0.25-0.5 ml 3 times a day intramuscularly. After the calcium and magnesium levels are stably normalised, Parathyreoidin is replaced by 0.5% alcohol solution of vitamin D_2.

EFFECT: using the method enables eliminating hypocalcemia considerably faster, recovering normal blood 25(OH)D that prevents recurrent convulsions.

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