FIELD: biotechnologies.
SUBSTANCE: in a compound of formula 
,
X means N or CH, R1 means hydrogen or cyano, R2 means saturated 4-7-membered residue of heterocyclyl, which is bound through a nitrogen atom that contains 1 to 2 heteroatoms chosen from N and O. Besides, heterocyclyl residue can be replaced with one substituent chosen from a group consisting of C3-C6-cycloalkyl, or with 1-4 fluorine atoms. The invention also refers to a method for obtaining compounds and to a medicine on their basis.
EFFECT: compounds can be used for production of a medicine suitable for being used in a method of treatment or prophylaxis of cardiovascular diseases, cardiac insufficiency, anemia, chronic diseases of kidneys and kidney failure.
16 cl, 1 tbl, 29 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HEMATOLOGIC DISEASES, USE THEREOF, DRUG AND METHOD OF TREATING AND/OR PREVENTING | 2012 |
|
RU2611012C2 |
| PIPERIDINYLPYRAZOLOPYRIMIDINONES AND USE THEREOF | 2015 |
|
RU2713937C2 |
| SUBSTITUTED 4-ARYL-1,4-DIHYDRO-1,6-NAPHTHYRIDINE AMIDES AND USE THEREOF | 2008 |
|
RU2470932C9 |
| NEW CYCLOPENTA[B]BENZOFURANYL DERIVATIVES AND APPLICATION THEREOF | 2005 |
|
RU2415847C9 |
| SUBSTITUTED OXOPYRIDINE DERIVATIVE | 2019 |
|
RU2792645C2 |
| NEW AZAQUINOLINE DERIVATIVES | 2018 |
|
RU2773290C2 |
| COMPOUNDS BASED ON PYRAZOLOPYRIDINONE | 2018 |
|
RU2806751C2 |
| PYRAZOLO[1,5-A]PYRIMIDINYLCARBOXAMIDES AND THEIR USE FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS | 2017 |
|
RU2799332C2 |
| COMPOUNDS BASED ON PYRAZOLOPYRIDINONE | 2018 |
|
RU2806625C2 |
| ACYLATED NONA-DEPSIPEPTIDES AS LYSOBACTIN DERIVATIVES | 2005 |
|
RU2414477C2 |
