FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology and microbiology. What is presented is a method for preparing a microgravimetric immunosensor. A surface of a quartz crystal resonator is activated first by plasma spray coating with polyethylene imine of molecular weight less than 10000 Da for 10 s in a vacuum unit at UHF field power 30 Wt. Thereafter, immunoglobulins from a solution with the protein concentration of 0.125 mg/ml are immobilised on the activated surface of the quartz crystal resonator. That is followed by washing in distilled water and drying in an air flow.
EFFECT: method enables preparing the immunosensor used for the purpose of the detection of infectious agents with the sensitivity of 1×103-1×104 mln. cells/ml and preserving the specific activity for.
3 cl, 3 ex.
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