METHOD AND DEVICE FOR PREDICTION OF PHARMACEUTICAL EFFECTIVENESS OF DRUG PREPARATION OF HUMANISED TNFα ANTIBODIES FOR TREATING RHEUMATOID ARTHRITIS Russian patent published in 2014 - IPC C12Q1/68 C12M1/34 

Abstract RU 2511394 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to molecular biology and pharmacology. What is presented is a method for the prediction of the pharmaceutical effectiveness of adalimumab for treating rheumatoid arthritis, wherein the method involves measuring a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA in a sample taken from a subject, and determining if adalimumab is effective for rheumatoid arthritis in a subject on the basis of a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA considered as a value.

EFFECT: method may be used in medicine in treating rheumatoid arthritis.

3 cl, 2 dwg, 8 tbl

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RU 2 511 394 C2

Authors

Tsudzaka Kensej

Dates

2014-04-10Published

2010-10-26Filed