FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to molecular biology and pharmacology. What is presented is a method for the prediction of the pharmaceutical effectiveness of adalimumab for treating rheumatoid arthritis, wherein the method involves measuring a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA in a sample taken from a subject, and determining if adalimumab is effective for rheumatoid arthritis in a subject on the basis of a level of at least one of ADAMTS4 iRNA and ADAMTS5 iRNA considered as a value.
EFFECT: method may be used in medicine in treating rheumatoid arthritis.
3 cl, 2 dwg, 8 tbl
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