METHOD OF PRODUCING 2-(2-THIENYL)PYRROLE Russian patent published in 2014 - IPC C07D409/04 

Abstract RU 2514945 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 2-(2-thienyl)pyrrole, which involves reacting 2-acetylthiophene with hydroxylamine, potassium hydroxide and acetylene in a medium of dimethyl sulphoxide; the process is carried out at atmospheric pressure and temperature of 80-120°C for 3-5 hours, with molar ratio 2-acetylthiophene:hydroxylamine chloride:potassium hydroxide of 1:1-1.2:2-2.5, using acetylene as the saturated solution in dimethyl sulphoxide, and hydroxylamine is generated directly in the reaction medium from hydroxylamine chloride and potassium hydroxide.

EFFECT: novel selective method of producing said compound, which is simple and environmentally safe.

3 cl, 8 ex

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RU 2 514 945 C1

Authors

Trofimov Boris Aleksandrovich

Mikhaleva Al'Bina Ivanovna

Shmidt Elena Jur'Evna

Protsuk Nadezhda Il'Inichna

Ivanov Andrej Viktorovich

Dates

2014-05-10Published

2012-11-29Filed