METHOD FOR OBTAINING VINYL ETHERS OF AMINOPHENOLS Russian patent published in 2018 - IPC C07C217/84 C07C213/06 

FIELD: chemistry.

SUBSTANCE: invention relates to an improved method for obtaining vinyl ethers of the aminophenols of the general formula (I). Connections are used as building blocks in organic synthesis and can be used as intermediates for obtaining biologically-active compounds, for example with antipyretic, analgesic, or antiviral action against herpes, or to obtain drugs for agriculture or as oxygenate antiknock additives to gasoline, or for obtaining ion exchange resins and semiconductors. Compounds of the general formula (I) , where R¹, R² - hydrogen or alkyl, are obtained by vinylating the corresponding aminophenol with acetylene under pressure in the presence of a base in a solvent containing water. When cetylene under a pressure of 11-18 ATM is fed to the reactor containing a mixture of aminophenol and the base or phenolate of aminophenol obtained from aminophenol and the base, in solvent, which is use as dimethyl sulfoxide containing 10-30 vol. % of water. The process is carried out under a pressure of 14-26 atm. when heated to 80-110°C. In this case, lithium or sodium or potassium hydroxides are used as the base in the concentration of 29-100 moll. % to the initial aminophenol.

EFFECT: method allows, at moderate temperature and pressure for 3-4 hours to increase the yield of target vinyl ethers and reduce production costs.

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