NOVEL COMPOUNDS OF REVERSE TURN MIMETICS, METHOD OF THEIR MANUFACTURING AND APPLICATION Russian patent published in 2014 - IPC C07D487/04 A61K31/495 A61P35/02 

Abstract RU 2515983 C2

FIELD: chemistry.

SUBSTANCE: described are novel pyrazine triazinone derivatives of general formula wherein Ra represents C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkinyl; Rb represents phenyl, substituted with acyl, alkoxy, hydroxyl, nitro, NH2, thioalkyl group or -C(=O)Re, where Re is C1-C6 alkyl, or group -C(=O)Re, where Re represents C1-C6 alkyl or cyclopropyl and Rp represents -H, -PO3H2, -HPO3-Na+, -PO32-Na2+, pharmaceutical composition, containing thereof, and method of treating acute myeloleukosis.

EFFECT: novel compounds represent reverse turn mimetics and can be applied in medicine.

9 cl, 1 dwg, 3 tbl, 24 ex

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RU 2 515 983 C2

Authors

Dzung Kiung-Jun

Chung Dzae Uk

Dzeong Min-Vook

Dzung Khi-Kiung

La Khiun-Dzu

Ma Sang-Kho

Li Jong-Sil

Dates

2014-05-20Published

2010-04-14Filed