FIELD: chemistry.
SUBSTANCE: described are novel pyrazine triazinone derivatives of general formula wherein Ra represents C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkinyl; Rb represents phenyl, substituted with acyl, alkoxy, hydroxyl, nitro, NH2, thioalkyl group or -C(=O)Re, where Re is C1-C6 alkyl, or group -C(=O)Re, where Re represents C1-C6 alkyl or cyclopropyl and Rp represents -H, -PO3H2, -HPO3 -Na+, -PO3 2-Na2 +, pharmaceutical composition, containing thereof, and method of treating acute myeloleukosis.
EFFECT: novel compounds represent reverse turn mimetics and can be applied in medicine.
9 cl, 1 dwg, 3 tbl, 24 ex
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Authors
Dates
2014-05-20—Published
2010-04-14—Filed