TETRAHYDROINDENOINDOLE COMPOUNDS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION SHOWING ANTIOXIDANT ACTIVITY, ANTIOXIDANT COMPOSITION AND A METHOD OF STABILIZATION OF COMPOUNDS EXHIBITING SENSITIVITY TO OXIDATION Russian patent published in 1998 - IPC

Abstract RU 2104270 C1

FIELD: organic chemistry. SUBSTANCE: product: cis-4b,5,9b,10-tetrahydro-5-ethyl-8-($$$N-diethylamino)-inde- -no-[1,2-b] -indole, yield is 65%; compound is unstable and becomes blue and then dark-red in air. Product: cis-4b, 5,9b,10-tetrahydro-5-methyl-8-tert.-butylindeno-[1,2-b]- -indole, yield is 96%, m. p. is 74 C. The synthesized compounds can be used as hydrophobic antioxidants for free radicals quenching in lipids or lipid double phases and for stabilization of compounds subjected to oxidative destruction. EFFECT: improved method of synthesis. 20 cl, 3 tbl

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RU 2 104 270 C1

Authors

Malkol'M Sehjnsberi[Gb]

Khovard Dzh.Shertser[Us]

Dates

1998-02-10Published

1990-06-20Filed