FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a crystalline salt of (1R*,2R*,4R*)-2-(2-{[3-(4,7-dimethoxy-1H-benzoimidazol-2-yl)propyl]methylamino}ethyl)-5-phenylbicyclo[2.2.2]oct-5-en-2-yl isobutyric acid ester. Also, the invention refers to a pharmaceutical composition of the above crystalline salt and using the above crystalline salt for preparing the pharmaceutical composition.
EFFECT: what is prepared is the crystalline salt of (1R*,2R*,4R*)-2-(2-{[3-(4,7-dimethoxy-1H-benzoimidazol-2-yl)propyl]methylamino}ethyl)-5-phenylbicyclo[2,2,2]oct-5-en-2-yl isobutyric acid ester that can be effective as a L/T-type calcium channel blocker.
15 cl, 11 dwg, 10 tbl, 6 ex
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