BENZIMIDAZOLE DERIVATIVES USEFUL AS T/L CHANNEL BLOCKERS Russian patent published in 2013 - IPC C07D235/14 A61K31/4184 A61P9/00

Abstract RU 2478095 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to compounds of formula (I) or pharmaceutically acceptable salts of such a compound, where R¹ is an unsubstituted phenyl; R² is -CO-R²¹; R²¹ is C_1-5alkyl; m equals 3; p equals 2 or 3; and R³ is hydrogen. The invention also relates to specific compounds of formula ,

a pharmaceutical composition based on the compound of formula (I) and use of the compound of formula (I).

EFFECT: novel compounds which are useful as T/L channel blockers are obtained.

6 cl, 1 tbl, 8 ex

Similar patents RU2478095C2

Title	Year	Author	Number
(1R,2R,4R*)-2-(2-{[3(4,7-DIMETHOXY-1H-BENZOIMIDAZOL-2-YL)PROPYL]METHYLAMINO}ETHYL)-5-PHENYLBICYCLO[2,2,2]OCT-5-EN-2-YL ISOBUTYRIC ACID SALTS	2009	Shtefan Abele Stefani Kombe Zhak-Aleksis Fjunel' Kurt Khil'Pert Fransis Juble Katarina Rajkhenbehkher Dorte Renneberg Markus Fon Raumer	RU2516247C2
BRIDGE SIX-MEMBER CYCLIC COMPOUNDS	2008	Khil'Pert Kurt Juble Fransis Renneberg Dorte	RU2503663C2
N-DIHYDROALKYLSUBSTITUTED 2-OXOIMIDAZOLE DERIVATIVES	2006	Khasimoto Masaja Ivasava Josikadzu Kavamoto Khirosi Okhta Khisasi Odzaki Satosi Sagara Takesi Sakokh Khiroki Satokh Atsusi	RU2414456C2
SECONDARY AMINES AS RENIN INHIBITORS	2007	Betsenkon Oliv'E Bur Daniel' Korminbef Oliv'E Djub Daniel' Grizostomi Korinna Makdonal'D Duajt Makkej Dehn Pauehll Dehvid Remen Ljubosh Rishar-Bildstejn Sil'Vija Shajgetts Dzhon Ter'En Mishel' Veller Tomas	RU2425032C2
CONDENSED QUINOLINE DERIVATIVE AND USE THEREOF	2005	Kadzino Masakhiro Kherd Nikolas Uill'Jam Tarui Naoki Banno Khirosi Kavano Jasukhiko Inatomi Nobukhiro	RU2384571C2
SUBSTITUTED DIAMINO-CARBOXAMIDE AND DIAMINO-CARBONITRILE PYRIMIDINE DERIVATIVES, THEIR COMPOSITIONS AND METHODS OF TREATMENT USING THEM	2012	Bennett Brajdon L. Elsner Yan Erdman Pol Khilgraf Robert Lebren Lori Enn Makkarrik Meg Mogkhaddam Mekhran F. Nejdzhi Mark A. Norris Stefan Pejzner Devid A. Sloss Meriann Romanov Uilliam Dzh. Satokh Jositaka Tike Dzhejeshri Joon Von Khiung Delgado Mersedes	RU2625309C2
MODULATION OF INFLAMMATORY AND METASTATIC PROCESSES	2005	Li Sang Kh. Khejz Karla K.	RU2377988C2
DERIVANTS OF BICYCLO[2, 2, 1] HEPT-7-YLAMINE AND THEIR APPLICATIONS	2006	Finch Garri Rehj Nikolas Charl'Z Bull Richard Dzhejms Van Nil Monik Bodil Dzhenningz Ehndrju Stefen Robert	RU2442771C2
SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, SYNTHESIS AND APPLICATION METHOD	2010	Ivashchenko Aleksandr Vasil'Evich Bychko Vadim Vasil'Evich Mit'Kin Oleg Dmitrievich	RU2452735C1
LIGANDS OF NICOTINE RECEPTOR α, THEIR OBTAINING AND APPLICATION	2005	Ngujen Truk Min Se Vehn'Ge Shumakher Richard Kherbert Brajan Tekhim Ashok	RU2418797C2

RU 2 478 095 C2

Authors

Juble Fransis

Khil'Pert Kurt

Renneberg Dorte

Dates

2013-03-27—Published

2009-04-23—Filed