FIELD: organic chemistry, medicine, oncology, pharmacy.
SUBSTANCE: invention relates to new derivatives of acridine of the formula (1): 
wherein R, R1, R2 and R3 mean hydrogen atom; Z means oxygen or sulfur atom; X means nitrogen atom or C-R5 wherein R5 means hydrogen atom; n = 2; m = 0; R4 means (C1-C3)-alkyl residue that can be substituted with aryl, (C4-C10)-heteroaryl and other substitutes, (C6-C10)-aryl and others, and to their pharmaceutically acceptable salts. Compounds of the formula (1) possess an anti-tumor activity and can be used as an active component of the medicinal agent.
EFFECT: improved preparing method, valuable medicinal properties of compounds and composition.
9 cl, 1 tbl, 20 ex
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