METHOD OF PRODUCING QUINAZOLINONE DERIVATIVES Russian patent published in 2014 - IPC C07D239/91 C07D471/04 

FIELD: chemistry.

SUBSTANCE: invention relates to an improved method of producing quinazoline derivatives of structural formula I:

,

where values of radicals R₁-R₆, R₈, W, P are given in the claim. The method involves reacting an aldehyde of formula II:

with ethylene carbonate to form a compound of formula III:

and reacting a compound of formula III with a compound of formula IV:

to form a compound of formula I. The invention also relates to methods of producing derivatives of the compound of formula I of structural formulae VI and VIII.

EFFECT: said methods enable to obtain products with low content of impurities and high output.

23 cl, 7 ex