FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing glycoprotein which is uniform in terms of functions derived from a sugar chain (e.g., blood half-life) and physiological activity units, i.e., a glycoprotein, having uniform amino acid sequence, sugar chain structure and higher-order structure, physiological activity, a method for screening for glycoprotein and a method of producing a mixture of glycoproteins.
EFFECT: high efficiency of the method.
6 cl, 37 dwg, 4 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PROCESS FOR PREPARATION OF GLYCOPEPTIDE HAVING SIALYLATED SUGAR CHAIN, AND METHOD FOR PRODUCING SIALYL GLYCOASPARAGINE | 2012 |
|
RU2586524C2 |
| GLYCATED PEPTIDE GLP-1 | 2009 |
|
RU2543157C2 |
| METHOD OF PRODUCING PEPTIDE | 2008 |
|
RU2478105C2 |
| NEW COMPOSITIONS OF EXENDINE AGONISTS AND METHODS OF THEIR ADMINISTRATION | 2000 |
|
RU2242244C2 |
| GLP-1 PEPTIDE HAVING ATTACHED OLIGOSACCHARIDE CHAIN | 2008 |
|
RU2539829C2 |
| GLYCOSYLATED POLYPEPTIDES AND MEDICINAL COMPOSITIONS CONTAINING THESE POLYPEPTIDES | 2012 |
|
RU2624034C2 |
| GLYCOSYLATED POLYPEPTIDES AND MEDICINAL COMPOSITIONS CONTAINING THESE POLYPEPTIDES | 2012 |
|
RU2627184C2 |
| ANALOGUES OF INSULIN-LIKE GROWTH FACTOR-1 (IGF-1), CONTAINING AMINO ACID SUBSTITUTION IN POSITION 59 | 2010 |
|
RU2511577C2 |
| ANTIBODY AND DRUG CONJUGATES (ADC) AND ANTIBODY AND PRODRUG CONJUGATES (APDC) CONTAINING ENZYMATICALLY CLEAVABLE GROUPS | 2016 |
|
RU2751512C2 |
| ANTI-MUC1 DRUG CONJUGATE | 2019 |
|
RU2804703C2 |
