GLYCOSYLATED POLYPEPTIDES AND MEDICINAL COMPOSITIONS CONTAINING THESE POLYPEPTIDES Russian patent published in 2017 - IPC C07K19/00 C07K14/655 C07K1/107 C07K17/10 C07K17/06 C07H3/06 A61K38/31 A61K47/36 A61P5/02 A61P1/00 

Abstract RU 2624034 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to production of glycosylated polypeptides having affinity for somatostatin receptors and can be used in medicine for somatostatin-related diseases treatment or prevention. SRIF14 and SRIF28 glycosylated polypeptides are obtained by Asn or Cys glycosylation.

EFFECT: invention provides preparation of glycosylated polypeptides having an affinity for somatostatin receptors and better stability in blood compared to somatostatin.

14 cl, 19 dwg, 10 tbl, 88 ex

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RU 2 624 034 C2

Authors

Otiaj Khirofumi

Simoda Tajdzi

Fukae Kadzukhiro

Maeda Masatosi

Isij Kadzuyuki

Esida Kenta

Tedzuka Katsunari

Tadzuru Kejsuke

Dates

2017-06-30Published

2012-09-03Filed