FIELD: chemistry.
SUBSTANCE: invention relates to the field of antimicrobial preparations and deals with compositions, which contain an antimicrobial agent and a compound, which is efficient for enhancement of the antimicrobial agent action. A composition for prevention and/or treatment of oral cavity diseases contains a carrier, an antimicrobial preparation and a compound, selected from the group of chalcones, consisting of 3-(4'-hydroxy-3'-methoxyphenyl)-1-(2'-hydroxy-5'-methoxyphenyl)prop-2-en-1-one, 3-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-prop-2-en-1-one, 3-(2",3"-dimethoxyphenyl)-1-furan-2-yl-prop-2-en-1-one, 3-(2",5"-dimethoxyphenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one and their mixtures. The composition is preferably made in the form of a tooth-cleaning preparation.
EFFECT: application of the said chalcones in a combination with antimicrobial preparations considerably enhances efficiency of the antimicrobial preparations.
15 cl, 12 tbl, 16 ex
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