METHOD FOR PREDICTION OF PREVENTIVE EFFECTIVENESS IN ACUTE POSTOPERATIVE PANCREATITIS IN ONCOLOGICAL PATIENTS Russian patent published in 2014 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for assessing effectiveness of pharmacotherapy aiming at preventing acute postoperative pancreatitis in abdominal surgeries involving splenectomy. Substance of a method: on the first postoperative day, a patient's blood plasma is examined for total BAEE-esterase activity and α-1-proteinase inhibitor activity; a coefficient of 'BAEE-esterase activity/α-1-proteinase inhibitor is calculated. If the derived coefficient is less than 20 units, the applied method for preventive treatment is predicted to be effective, while the value increasing above 20 units shows ineffectiveness of preventive treatment. The presented method is implemented on the day of blood sampling - on the first postoperative day that enables taking adequate measures in a combination with the measures to prevent developing acute postoperative pancreatitis.

EFFECT: invention provides specificity of the method for prediction of preventive effectiveness of 84,1%, and for prediction of ineffectiveness of 98,7%.

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