PREPARATION AND CRYSTALLISATION OF S-[2-[1-(2-ETHYLBUTYL) CYCLOHEXYLCARBONYLAMINO]-PHENYL]-2-METHYLTHIOPROPIONATE Russian patent published in 2014 - IPC C07C327/30 

Abstract RU 2523280 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a method for preparing S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]-2-methylthiopropionate of the formula (I), which is applicable as a pharmaceutically active compound. The method involves a reaction of the compound of the formula (II) and isobutyric anhydride and a reducing agent.

EFFECT: method enables preparing high-yield S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]-2-methylthiopropionate.

10 cl, 12 ex

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Authors

Deklan Kostello

Dzherard Dzhon Kharnett

Pirmin Khidber

Urzula Khoffmann

Tomas Makkarti

Rajnkhard Rents

Dennis A. Smit

Timoti Smit

Dates

2014-07-20Published

2010-06-28Filed