FIELD: medicine.
SUBSTANCE: peripheral venous blood of pregnant women suffering from threatening recurrent miscarriage is examined. The peroxynitrite and NO-tyrosine concentrations are measured in 6-12 weeks of gestation. That is followed by calculating a peroxynitrite/NO-tyrosine ratio. If the derived value is less than 11%, a short-term effect of the standard preserving therapy is predicted. If the value falls within the range of 11.0% or more, a prolonged effect of the standard therapy and a gestation course with no threatening miscarriage in the 2nd and 3rd trimesters are predicted.
EFFECT: more accurate prediction, enabled timely correction of medical and preventive measures for the purpose of prevention of late miscarriage; the method is easy to implement and properly reproducible.
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