FIELD: medicine.
SUBSTANCE: balanced ration to be gradually changed by cholesterol and pork fat is fed in male rats aged more than one year. Vitamin D2 in an amount of 35,000 IU/kg to 60,000 IU/kg of body weight is orally introduced. The above manipulations are carried out with an underlying exposure to stress factors: noise, varying photoperiod and periodic hypoxia.
EFFECT: method provides inducing pathoanatomical, haematological, biochemical and histological changes specific for atherosclerosis and close to those in a human.
4 ex, 2 tbl
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