METHOD OF SIMULATING ATHEROSCLEROSIS Russian patent published in 2013 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: for the purpose of diagnosing, preventing and treating the same disease, a cholesterol powder in the amount of 1%, margarin 10%, mercazolilum 10 mg/kg and vitamin D 2.5 IU per kg of body weight is added to the laboratory rats' feed. That is combined with performing an operation of ligating a left renal pedicle with a non-absorbable suture and underrunning a right upper pole with 2/3 of the organ being preserved.

EFFECT: method is easy to implement, causes no animal death; it represents an adequate model of an endothelial damage and atherosclerotic process development.

12 dwg, 4 tbl, 1 ex