METHOD OF ENDOVASCULAR PREVENTION OF ENDOTOXINEMIA IN LAPAROSCOPIC INTERVENTIONS IN PATIENTS WITH ACUTE ABDOMINAL PATHOLOGY, COMPLICATED WITH PERITONITIS Russian patent published in 2014 - IPC A61M25/00 A61K31/167 A61K31/455 A61K33/14 A61P41/00 

FIELD: medicine.

SUBSTANCE: at the first stage a puncture of the right femoral artery or the right radial artery by Seldinger is performed with further successive catheterisation of the mouth of superior and inferior mesenteric arteries. After that, infusion of 0.5 ml of a 15% solution of xantinol nicotinate and 1.0 ml of a 2% lidocaine solution, diluted in 20.0 ml of a 0.9% solution of sodium chloride is performed. Introduction is carried out under X-ray control.

EFFECT: prevention of endotoxinemia development in the said category of patients due to reduction of spasm of the microcirculatory bed of the small intestine wall, and reduction of oedema and ischemia of the intestine mucosa, blocking the passage of nerve impulses to the intestine wall, which results in reduction of the intestine atony and reduction of translocation of endotoxins from the intestine lumen into the bloodstream.

1 ex