DIAGNOSTIC TECHNIQUE FOR PULMONARY THROMBOEMBOLISM Russian patent published in 2014 - IPC G01N33/52 

FIELD: medicine.

SUBSTANCE: technique involves preparing a patient's blood serum sample by drying blood serum, milling the dry deposition and suspending in Vaseline oil. The prepared sample is analysed by IR-spectroscopy by determining a peak height of absorption bands with maxima 1165; 1160; 1150; 1100; 1070; 1050, and 1025 cm^-1. And the peak height relations are calculated: the relation of the peak height with maximum 1160 cm^-1 to the peak height with maximum 1165 cm^-1; the relation of the peak height with maximum 1165 cm^-1 to the peak height with maximum 1070 cm^-1; the relation of the peak height with maximum 1165 cm^-1 to the peak height with maximum 1150 cm^-1, the relation of the peak height with maximum 1165 cm^-1 to the peak height with maximum 1050 cm^-1, the relation of the peak height with maximum 1100 cm^-1 to the peak height with maximum 1050 cm^-1, the relation of the peak height with maximum 1025 cm^-1 to the peak height with maximum 1165 cm^-1. The derived values are used to draw a differential diagnostic profile of the patient's blood serum sample to produce a plane polygon formed by 6 beams corresponding to 6 relations and to compare the above polygon to a polygon that is a reference differential diagnostic profile of pulmonary thromboembolism, wherein 6 relations make: 1 (1.85±0.26), 2 (0.28±0.13), 3 (0.39±0.07), 4 (0.25±0.13), 5 (0.58±0.10), 6 (4.47±1.70). If the derived patient's differential diagnostic profile has a similarity with the reference profile, and all 6 relations of the patient's blood serum sample coincide with the reference relations, pulmonary thromboembolism is diagnosed in the patient.

EFFECT: invention possesses high accuracy, easy to implement, and requires no heavy material and time expenses; it enables diagnosing thromboembolism of all pulmonary arteries both in the presence of clinically significant symptoms of the disease, and in the absence thereof.

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