SYSTEM OF ACTIVE INGREDIENT DELIVERY Russian patent published in 2014 - IPC A23L1/22 C07D285/00 

FIELD: chemistry.

SUBSTANCE: delivery system in the form of a solid dispersion contains a carrier material, consisting mainly of a crystalline material of a matrix and a solid active ingredient, which has structure (I) or its salts. The solid active material is dispersed in the matrix of the carrier material. The method of obtaining the delivery system includes the formation of the carrier material melt, introduction of the active ingredient, which has the structure (I) into the melt, the formation in the melt of a melted mixture, containing an emulsion, dispersion, solution or suspension of the active ingredient, the formation of separate particles, cooling the separate particles, optional crushing of the separate particles and the formation of the solid dispersion of the active substance in the delivery system matrix.

EFFECT: improvement of a rate of dissolution of the lowly dissolving solid compound 1.

11 cl, 1 tbl, 2 ex