LIPOSOME SUSPENSION STABILISER AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2014 - IPC A61K31/722 C08B37/08 A61K9/127 

Abstract RU 2529179 C1

FIELD: chemistry.

SUBSTANCE: stabiliser includes modified chitosan which is obtained by modifying chitosan particles located in an emulsion of an organic solvent - water, with pH 6.0-6.5, by first reacting a mixture consisting of a carboxylic acid in an organic solvent and a condensing agent, and then with an organic base, wherein the carboxylic acid used is either palmitic acid or stearic acid or dodecanoic acid, the condensing agent used is a mixture of hydroxysuccinimide and an aliphatic carbodiimide or formaldehyde and an aliphatic isocyanide, and the organic base used is triethylamine.

EFFECT: effective liposome composition stabiliser which can be obtained using a simple method.

8 cl, 3 tbl, 5 ex, 7 dwg

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RU 2 529 179 C1

Authors

Ponomarev Vladislav Sergeevich

Mironov Maksim Anatol'Evich

Tokareva Marija Igorevna

Ivantsova Marija Nikolaevna

Rusinov Vladimir Leonidovich

Matern Anatolij Ivanovich

Charushin Valerij Nikolaevich

Chupakhin Oleg Nikolaevich

Dates

2014-09-27Published

2013-04-23Filed