AGENT FOR TREATING A TUMOR AND A KIT CONTAINING A LIPOSOMAL COMPOSITION OF GEMCITABINE Russian patent published in 2020 - IPC A61K31/7068 A61K9/127 A61K31/337 A61P35/00 

Abstract RU 2738365 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention relates to an antitumour therapeutic agent and an antitumour kit. Antitumour therapeutic agent contains gemcitabine or its salt in liposome and nab-paclitaxel, wherein liposome-forming lipid contains cholesterols, wherein the molar cholesterol content with respect to the total amount of lipids forming the liposome ranges from 10 mol % to 35 mol %, liposome-forming lipid contains hydrogenated soya phosphatidyl choline and osmotic pressure of the internal aqueous phase of liposome 3 to 5 times greater than the osmotic pressure of the external aqueous phase of the liposome.

EFFECT: invention provides an excellent anticancer effect when compared with gemcitabine, taxane anticancer agent and their combined therapy, which are available on the market.

6 cl, 1 ex, 2 tbl, 1 dwg

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RU 2 738 365 C2

Authors

Kitahashi, Tsukasa

Mima, Shinji

Matsumoto, Takeshi

Sekiguchi, Takahiro

Mori, Mikinaga

Dates

2020-12-11Published

2016-11-01Filed