FIELD: medicine.
SUBSTANCE: group of inventions relates to a device and a method of detecting and/or quantitative determination of molecules in saliva and is intended for the determination of analytes in saliva. A microliquid device includes one or several areas of preliminarily processing, which include a surface, containing a molecule, capable of specific or non-specific binding with one or more of saliva components in a saliva sample, preventing the detection of one or more analytes, for specific or non-specific removal of a part of a fraction of the said saliva components in the saliva sample, preventing the detection of one or more analytes, with the molecule being hydroxyapatite or an antibody against mucin; and an area of detection, including a surface of a biosensor with the molecule, capable of specific binding of one or more analytes and providing the detection of one or more analytes, or one or more analytes and/or molecules, structurally relative to analyte and binding analyte-specific probes.
EFFECT: application of the microliquid device provides the method of detecting the presence of one or more analytes.
12 cl, 4 dwg, 4 ex
Title | Year | Author | Number |
---|---|---|---|
DETECTION METHODS AND SYSTEMS | 2008 |
|
RU2480768C2 |
BIOSENSOR COMPRISING METAL NANOPARTICLES | 2013 |
|
RU2658052C2 |
ANALYSIS METHOD AND DEVICE USING MAGNETIC PARTICLES | 2010 |
|
RU2595843C2 |
FAST BIOSENSOR WITH REAGENT LAYER | 2007 |
|
RU2482495C2 |
BIOSENSOR SYSTEM FOR ACTUATING MAGNETIC PARTICLES | 2009 |
|
RU2519655C2 |
UNIVERSAL BIOSENSOR SYSTEM FOR ANALYTE DETECTION | 2017 |
|
RU2737943C1 |
TARGET MOLECULE DETECTION IN SAMPLE | 2007 |
|
RU2444736C2 |
MAGNETIC RECOGNITION | 2007 |
|
RU2442169C2 |
EXCITING MAGNETIC SPHERES USING FEEDBACK FOR FTIR BASED BIOSENSOR | 2009 |
|
RU2526198C2 |
SYSTEM (VARIANTS) AND METHOD OF DETECTING ANALYTE PRESENCE IN LIQUID SAMPLE | 2011 |
|
RU2653451C2 |
Authors
Dates
2014-10-10—Published
2009-05-26—Filed