ANTI-ANGIOGENESIS THERAPY USED FOR TREATING BREAST CANCER Russian patent published in 2014 - IPC A61K39/395 A61K31/7068 A61P35/04 

Abstract RU 2531948 C2

FIELD: medicine.

SUBSTANCE: effective amount of a chemotherapeutic agent and anti-VEGF antibodies (bevacizumab), wherein the agent represents either (a) capecitabine, (b) docetaxel or Abraxane, (c) or antracycline, and wherein the anti-VEGF antibody is administered at 15 mg/kg. No other chemotherapeutic agent has been administered into the individual for treating local recurrent or metastatic breast cancer, and/or the above individual has not undergone adjuvant pre-chemotherapy accompanying a recurrence for 12 months or less after the last dose administered. There are also presented the anti-VEGF antibody, using the anti-VEGF antibody and kits containing the anti-VEGF antibody in a combination with the chemotherapeutic agent for treating metastatic breast cancer.

EFFECT: prolonged individual's lifespan with no disease progression.

40 cl, 6 dwg, 5 tbl, 1 ex

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RU 2 531 948 C2

Authors

Fajf Gvendolin

Fehn Si Chun'

Chzhou Sjan'

Dates

2014-10-27Published

2009-11-20Filed