METHOD OF OBTAINING SULPHATED DERIVATIVES OF ARABINOGALACTAN, POSSESSING ANTICOAGULANT AND HYPOLIPIDEMIC ACTIVITY Russian patent published in 2014 - IPC C08B37/00 

FIELD: chemistry.

SUBSTANCE: in the claimed method sulphated derivatives of arabinogalactan, separated from larix sibirica wood, are obtained by the interaction of arabinogalactan in a solvent with a sulphating agent with continuous mixing and a stable temperature not higher than +50°C for not more than 12 hours with the following separation, purification and drying of the product, as the sulphating mixture applied is dry potassium persulphate (K₂S₂O₈) in a solution of dimethylsulphoxide. Claimed is a novel effective method, which makes it possible to obtain sulphated AG derivatives both in acidic and in salt forms. A degree of biopolymer macromolecule substitution in terms of the quantitative sulphur content constitutes 9.3-14.2%.

EFFECT: obtained sulphated AG derivatives preserve structural organisation, water solubility and membranotropism of a natural polysaccharide and demonstrate a pharmacological activity.

4 cl, 1 dwg, 3 ex