ORGANOARSENIC COMPOUNDS AND METHODS OF TREATING CANCER Russian patent published in 2014 - IPC A61K31/285 A61K31/60 A61K31/455 A61K38/06 A61P35/00 

Abstract RU 2534606 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine, anti-cancer therapy, and concerns a method of treating lymphoma specified in diffuse large B-cell lymphoma, marginal zone lymphoma and nodular sclerosis Hodgkin lymphoma by means of an organic derivative of arsenic, such as darinaparsin (S-dimethylarsinoglutathione, SGLU-1):

or its pharmaceutically acceptable salt. The administration is performed once a day for five days every four weeks in a dose of 200-420 mg/m2, in particular intravenously. The invention also concerns using the above compound or its pharmaceutically acceptable salt for preparing the respective drug and pharmaceutical compositions.

EFFECT: group of inventions provides the effective treatment of the above group of diseases with similar or higher activity or lower toxicity as compared to arsenic oxide.

8 cl, 11 ex

Similar patents RU2534606C2

Title Year Author Number
N1-(4-(5-(CYCLOPROPYLMETHYL)-1-METHYL-1H-PYRAZOLE-4-YL)PYRIDINE-2-YL)CYCLOHEXANE-1,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF CK1 AND/OR IRAK1 FOR THE TREATMENT OF CANCER 2018
  • Li, Dansu
  • Snir-Alkalaj, Irit
  • Vakka, Jozef
  • Ben Neriakh, Jinon
  • Venkatak-Ialam, Avantika
RU2761457C2
CYANOTHIENOTRIAZOLODIAZEPINES AND METHODS FOR THEIR USE 2016
  • Bradner Dzhejms I.
  • Tsi Tszyun
  • Tanaka Minoru
  • Bakli Dennis
RU2750164C2
BENZIMIDAZOLES USED AS PROTEIN KINASE INHIBITORS 2006
  • Binch Khehjli
  • Mortimor Majkl
  • Robinson Dehniel
  • Stamos Din
  • Ehverit Sajmon
RU2415853C2
BENZO[b]THIOPHENE STING AGONISTS FOR TREATMENT OF CANCER 2018
  • Cemerski, Saso
  • Cumming, Jared, N.
  • Kopinja, Johnny, E.
  • Perera, Samanthi, A.
  • Trotter, Benjamin Wesley
  • Tse, Archie Ngai-Chiu
RU2771811C2
BIVALENT BROMODOMAIN INHIBITORS AND ROUTES OF USE THEREOF 2016
  • Tsi, Tszyun
  • Tanaka, Minoru
  • Roberts, Dzhastin, M.
  • Bradner, Dzhejms I.
RU2742035C2
COMBINATION THERAPY USING CC CHEMOKINE RECEPTOR 4 (CCR4) ANTAGONISTS AND ONE OR MORE CHECKPOINT INHIBITORS 2019
  • Li, Shijie
  • Mali, Venkat Reddy
  • Singh, Rajinder
  • Yang, Ju
  • Zhang, Penglie
RU2810717C2
HETEROCYCLIC COMPOUNDS AND USES THEREOF 2014
  • Chzhan Tszyayazhun
  • Buell Dzhon
  • Chan Katrina
  • Ibrakhim Prabkha N.
  • Lin Dzhek
  • Fam Fuongli
  • Shi Sonyuan
  • Spevak Vejn
  • Vu Guosyan
  • Vu Dzheffri
RU2680100C9
METHOD FOR ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY STRENGTHENING 2011
  • Khershberg Robert
RU2627660C2
COMBINED PRODUCTS CONTAINING TYROSINE KINASE INHIBITORS AND THEIR USE 2013
  • Tidt Ralf
  • Shatene-Rivode Kristian
  • Ito Moriko
  • Pen Bin
  • Gun In
  • Akimov Mikhail
RU2660354C2
BENZIMIDAZOLE DERIVATIVES AS ERBB TYROSINE KINASE INHIBITORS FOR TREATING CANCER 2015
  • Long, Yun
RU2741914C2

RU 2 534 606 C2

Authors

Shvarts Brajan Ehrik

L'Juis Dzhonatan

Komarnitskij Filip B.

Dates

2014-11-27Published

2009-08-14Filed