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2 534 995

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IPC

C07J53/00(2006-01-01)

A61K31/57(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2013131326/04, 2013-07-09

(24)

Start date

2013-07-09

(22)

Actual filing date

2013-07-09

(45)

Published

2014-12-10

(72)

Inventor

Levina Inna SolomonovnaKulikova Lidija EgorovnaZavarzin Igor' ViktorovichShimanovskij Nikolaj L'VovichSemejkin Aleksandr VladimirovichKareva Elena NikolaevnaFedotcheva Tat'Jana AleksandrovnaTikhonov Dmitrij AleksandrovichOdintsova Elena Valer'Evna

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Natsional'Nyj Issledovatel'Skij Meditsinskij Universitet Im. N.I. Pirogova Ministerstva Zdravookhranenija Rossijskoj Federatsii" Vpo Rnimu Minzdrava Rossii)

6-OXIMES OF 16(, 17(-CYCLOHEXANEPREGNENES HAVING CYTOTOXIC ACTIVITY TOWARDS HUMAN TUMOUR CELLS Russian patent published in 2014 - IPC C07J53/00 A61K31/57 A61P35/00

Abstract RU 2534995 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to 6-oximes of 16α, 17α- cyclohexanepregnenes of general formula I , where X+Y together form O or X=H, Y=OH; R=H or CH₃.

EFFECT: compounds have cytotoxic activity and can find application for treatment of malignant tumours.

3 cl, 3 tbl, 5 ex

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RU 2 534 995 C1

Authors

Levina Inna Solomonovna

Kulikova Lidija Egorovna

Zavarzin Igor' Viktorovich

Shimanovskij Nikolaj L'Vovich

Semejkin Aleksandr Vladimirovich

Kareva Elena Nikolaevna

Fedotcheva Tat'Jana Aleksandrovna

Tikhonov Dmitrij Aleksandrovich

Odintsova Elena Valer'Evna

Dates

2014-12-10—Published

2013-07-09—Filed