METHOD OF DETERMINING APOLIPOPROTEIN A1 AND APOLIPOPROTEIN IN BLOOD PLASMA Russian patent published in 2014 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: method includes transmitting variable-frequency ultrasound through a sample with distilled water and through a sample with blood plasma at two different temperatures; measuring the propagation speed of ultrasound through the sample and determining the relative propagation speed of ultrasound through the samples, using a pair of samples with distilled water and a pair of samples with blood plasma; temperature of one of the samples in the pair is kept lower than the other, but temperature of samples in a pair is kept equal in the range of 25-40°C; determining the absorption coefficient of ultrasound in distilled water and the absorption coefficient of ultrasound in blood plasma and relationship thereof with frequency in the range of 4-15 MHz, and the relationship between the speed of ultrasound in the blood plasma and temperature; determining apolipoprotein A1 and apolipoprotein B by solving a system of linear equations for two unknowns.

EFFECT: high accuracy and information value, faster analysis.

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