FIELD: biotechnologies.
SUBSTANCE: invention represents a producing method of cream containing fusidic acid, which involves a stage of application of sodium fusidate as an initial active ingredient and conversion of the above sodium fusidate in situ to fusidic acid in an oxygen-free medium by immediate addition of the acid to a cream base containing a preservative, an acid, a cosolvent, an emulsifier, a wax-like product and water.
EFFECT: obtaining cream having high stability at storage and smaller particles of an active ingredient.
9 cl, 11 tbl
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