FIELD: medicine.
SUBSTANCE: invention represents cream for skin infections, containing fusidic acid formed in situ in an oxygen-free medium with the use of sodium fusidate. The above cream contains fusidic acid prepared in situ by the conversion of sodium fusidate with adding acid slowly, with a particle size of the active substance of 2.33 mcm to 16.3 mcm, and the cream base containing at least one ingredient of each type: primary and secondary emulsifying agents specified in a group containing ketostearyl alcohol, ketomacrogol-1000, Polysorbate-80 and Span-80, paraffin as wax, a combined dissolving agent specified in a group including propylene glycol, hexylene glycol, polyethylene glycol 400, nitric acid or lactic acid and water.
EFFECT: invention provides high stability of the active ingredient throughout the whole shelf life.
10 cl, 16 tbl
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