METHOD OF APPLYING VEGETABLE POLYSACCHARIDE AS RADIOPROTECTOR AND STIMULATOR OF COLONY FORMATION OF SPLEEN STEM CELLS IN IRRADIATED ANIMALS Russian patent published in 2014 - IPC A61K36/81 A61K31/715 A61P39/00 

Abstract RU 2537033 C1

FIELD: medicine.

SUBSTANCE: invention relates to radiation and experimental biology, biotechnology and medicine, namely to means of radiological protection and to stimulators of colony formation of stem cells. Invention can be used in research and clinical practice for protection of living organisms in case of exposure to ionising radiation, in emergency and military medicine, in case of emergency situations as means for protection against radiation injury. Claimed is application of preparation gamma-plant as radioprotector with colony-stimulating properties for increasing survival and improving state of organisms, subjected to irradiation. Gamma-plant is non-toxic polysaccharide of vegetable origin, registered by Ministry of Health of the Russian Federation and allowed for medical application; Gamma-plant is included into Russian Pharmacopoeia in section FG-9 "non-narcotic analgesics".

EFFECT: invention makes it possible to increase efficiency of colony formation of stem cells in spleen 2,0-2,3 times, increases survival of experimental animals to 95% with coefficient of dose reduction factor DRF, equal 2-2,2.

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RU 2 537 033 C1

Authors

Generalov Evgenij Aleksandrovich

Dates

2014-12-27Published

2013-10-29Filed