FIELD: medicine.
SUBSTANCE: what is used is botulinum toxin A in a dose of 20-35 Units administered into 4 points of 1, 5, 7 and 11 o'clock of the internal anal sphincter in a combination with subcutaneous administration of botulinum toxin 5-7 Units under the fissure from its distal end. Besides, a condition medium of mesenchymal stem cells in an amount of 20-30 ml is introduced into the rectum.
EFFECT: higher clinical effectiveness in the anal fissure and lower number of therapeutic injuries.
3 ex
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