METHOD FOR ANAL FISSURE TREATMENT Russian patent published in 2017 - IPC A61B17/00 A61K35/00 A61P37/02 

FIELD: medicine.

SUBSTANCE: for treatment of a chronic anal fissure, it is excised along with the surrounding scar tissue and the guard tubercle by two half-moon incisions within healthy tissues. 0.1-0.2 ml doses of autoplasma, enriched with platelet growth factors, is injected into the wound walls and bottom with a grid of 3-4 mm. Wound edges are separated by a rectal mirror. A film of enriched autoplasm is applied to the wound bottom. Enriched autoplasm in a volume of 1 ml is injected under the wound, to a depth of 5-7 mm. Botulinum toxin A at a dose of 15-20 units is injected into the inner sphincter at three points to a depth of 5-7 mm. In case of back fissure, botulinum toxin is administered at 5, 7 and 12 hours, in case of front fissure - at 11, 1 and 6 hours. On the 4th day, the introduction of autoplasm is repeated.

EFFECT: reduces postoperative pain syndrome, increases the effectiveness of anal fissure treatment, reducing the risk of postoperative complications.

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