Show metadata Hide metadata

(19)

(11)

2 537 295

(13)

(51)

IPC

C07D487/04(2006-01-01)

A61K31/519(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2013148985/04, 2013-11-01

(24)

Start date

2013-11-01

(22)

Actual filing date

2013-11-01

(45)

Published

2014-12-27

(72)

Inventor

Chupakhin Oleg NikolaevichRusinov Vladimir LeonidovichUlomskij Evgenij NartsissovichSavateev Konstantin Valer'EvichBorisov Stepan SergeevichNovikova Natal'Ja AleksandrovnaLoginova Svetlana JakovlevnaBorisevich Sergej VladimirovichSorokin Pavel Vladimirovich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju Tsentr Biofarmatsevticheskikh Tekhnologij"

4-(2-HYDROXYETHOXY)METHYL)-5-METHYL-2-METHYLMERCAPTO-1,2,4-TRIAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE - SUBSTANCE HAVING ANTIVIRAL ACTION, METHOD FOR PRODUCTION AND USE THEREOF AGAINST WEST NILE FEVER AGENT Russian patent published in 2014 - IPC C07D487/04 A61K31/519 A61P31/12

Abstract RU 2537295 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically 4-((2-hydroxyethoxy)methyl)-5-methyl-2-methylmercapto-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one of formula (I) . The invention also relates to a method of producing and using said compound to treat West Nile fever.

EFFECT: obtaining a novel compound with useful biological activity.

3 cl, 2 tbl, 4 ex

Similar patents RU2537295C1

Title	Year	Author	Number
2-METHYLSULPHANYL-6-NITRO-OXO-1,2,4-TRIAZOLO[5,1-c] [1,2,4]TRIAZINIDE L-ARGININIUM DIHYDRATE, POSSESSING ANTIVIRAL ACTIVITY, METHOD OF ITS OBTAINING AND APPLICATION FOR PREVENTION AND TREATMENT OF WEST NILE FEVER	2013	Chupakhin Oleg Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Savateev Konstantin Valer'Evich Borisov Stepan Sergeevich Novikova Natal'Ja Aleksandrovna Loginova Svetlana Jakovlevna Borisevich Sergej Vladimirovich Sorokin Pavel Vladimirovich	RU2536874C1
MEDICATION POSSESSING ANTI-VIRAL ACTIVITY AND CONTAINING 2-METHYLTHIO-5-METHYL-6-NITRO-1,2,4-TRIAZOLO[1,5-a]PYRIMIDIN-7(3H)-ON	2007	Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Charushin Valerij Nikolaevich Chupakhin Oleg Nikolaevich Loginova Svetlana Jakovlevna Borisevich Sergej Vladimirovich Khamitov Ravil' Avgatovich Maksimov Vladimir Alekseevich	RU2365591C2
SODIUM SALT OF 2-ETHYLTHIO-6-NITRO-1,2,4-TRIAZOLE[5,1-c]-1,2,4-TRIAZIN-7-ONE DIHYDRATE	2008	Chupakhin Oleg Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Charushin Valerij Nikolaevich Medvedeva Natal'Ja Rozyevna Kiselev Oleg Ivanovich Deeva Ehlla Germanovna Loginova Svetlana Jakovlevna Borisevich Sergej Vladimirovich Bondarev Vladimir Petrovich	RU2404182C2
AZOLOAZINE SALTS OF FLUOROQUINOLONES, POSSESSING ANTIBACTERIAL AND ANTIVIRAL ACTION	2014	Chupakhin Oleg Nikolaevich Charushin Valerij Nikolaevich Kotovskaja Svetlana Konstantinovna Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Bykov Vladimir Nikolaevich Stepanov Aleksandr Valentinovich Chepur Sergej Viktorovich Lebedeva Irina Kirillovna Tsikarishvili Georgij Varlamovich Kurpjakova Anna Fedorovna	RU2547835C1
3-BENZYL-5-METHYL-6-(PHENYLTHIO)-[1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7(3H)-ONE, WHICH HAS ANTIVIRAL ACTIVITY AGAINST THE SARS-CoV2 CORONAVIRUS	2022	Akulov Aleksej Aleksandrovich Kotovskaya Svetlana Konstantinovna Silaeva Anastasiya Igorevna Varaksin Mikhail Viktorovich Rusinov Vladimir Leonidovich Charushin Valerij Nikolaevich Pyankov Oleg Viktorovich Shipovalov Andrej Vladimirovich Kudrov Gleb Aleksandrovich Zajkovskaya Anna Vladimirovna Skarnovich Maksim Olegovich Filippova Ekaterina Igorevna	RU2808622C1
SODIUM SALT OF 2-METHYL-6-FLUORO-1,2,4-TRIAZOLO[5,1-c]-1,2,4-TRIAZIN-7(4H)-ONE DIHYDRATE, HAVING ANTIVIRAL ACTIVITY	2009	Chupakhin Oleg Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Medvedeva Natal'Ja Rozyevna Kiselev Oleg Ivanovich Deeva Ehlla Germanovna Sinjashin Oleg Gerol'Dovich Mamedov Vakhid Abdulla-Ogly	RU2493158C2
SODIUM SALT 5-METHYL-6-NITRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINE-7-ONE DIHYDRATE	2006	Chupakhin Oleg Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Charushin Valerij Nikolaevich Petrov Aleksandr Jur'Evich Kiselev Oleg Ivanovich	RU2330036C1
5-METHYL-6-NITRO-7-OXO-4,7-DIHYDRO-1,2,4-TRIAZOLO[1,5-ALPHA]PYRIMIDINIDE L-ARGININIUM MONOHYDRATE	2013	Chupakhin Oleg Nikolaevich Charushin Valerij Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Kotovskaja Svetlana Konstantinovna Kiselev Oleg Ivanovich Deeva Ehlla Germanovna Savateev Konstantin Valer'Evich Borisov Stepan Sergeevich	RU2529487C1
3-BUTYLTHIO-1-(BETA-D-2-DEOXYRIBOFURANOSYL)-5-PHENYL-(4H)-1,2,4-TRIAZOLE, SYNTHESIS, ANTI-HERPES VIRUS ACTION	2023	Konstantinova Irina Dmitrievna Fateev Ilya Vladimirovich Andronova Valeriya Lvovna Esipov Roman Stanislavovich Miroshnikov Anatolij Ivanovich Sasmakov Sobirdzhan Anarmatovich Azimova Shakhnoz Sadykovna Abdurakhmanov Zhaloliddin Mirdzhamilevich Ziyaev Abdukhakim Anvarovich Dolimov Khaetzhon Khakimzhon Ugli	RU2815137C1
4-((Z)-4'-HYDROXYBUTENE-2'-YL)-2-R-6-FURYL-1,2,4-TRIAZOLO[5,1-c][1,2,4]TRIAZINE-7-ONS	2008	Chupakhin Oleg Nikolaevich Rusinov Vladimir Leonidovich Ulomskij Evgenij Nartsissovich Charushin Valerij Nikolaevich Shestakova Tat'Jana Sergeevna Deev Sergej Leonidovich Rusinova Larisa Ivanovna Andronova Valerija L'Vovna Galegov Georgij Artem'Evich Karpenko Inna Leonidovna Jas'Ko Maksim Vladimirovich Kukhanova Marina Konstantinovna	RU2376307C1

RU 2 537 295 C1

Authors

Chupakhin Oleg Nikolaevich

Rusinov Vladimir Leonidovich

Ulomskij Evgenij Nartsissovich

Savateev Konstantin Valer'Evich

Borisov Stepan Sergeevich

Novikova Natal'Ja Aleksandrovna

Loginova Svetlana Jakovlevna

Borisevich Sergej Vladimirovich

Sorokin Pavel Vladimirovich

Dates

2014-12-27—Published

2013-11-01—Filed