FIELD: medicinal chemistry.
SUBSTANCE: invention relates to 3-benzyl-5-methyl-6-(phenylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one of formula 3a.
EFFECT: 3-benzyl-5-methyl-6-(phenylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one, which has a pronounced inhibitory effect against hCoV-19/Russia/Vologda-171613-1208/2020 SARS-CoV2 virus strain.
1 cl, 2 dwg, 1 tbl
Title | Year | Author | Number |
---|---|---|---|
APPLICATION OF A TRICYCLIC SULPHUR-CONTAINING DERIVATIVE OF 1,2-DIHYDROQUINOLINE FOR INHIBITING THE REPLICATION OF BETACORONAVIRUSES, INCLUDING SARS-COV-2 | 2021 |
|
RU2780247C1 |
PHARMACEUTICAL COMPOSITION, INCLUDING TRICYCLIC SULFUR-CONTAINING 1,2-DIHYDROQUINOLINE DERIVATIVE FOR INHIBITION OF REPLICATION OF BETA CORONAVIRUSES, INCLUDING SARS-CoV-2, AND METHOD OF ITS USE | 2021 |
|
RU2814434C1 |
METHOD OF PRODUCING A TRICYCLIC SULFUR-CONTAINING DERIVATIVE OF 1,2-DIHYDROQUINOLINE FOR INHIBITING REPLICATION OF BETA-CORONAVIRUSES, INCLUDING SARS-CoV-2 | 2021 |
|
RU2819783C1 |
METHOD OF PRODUCING 5-SUBSTITUTED 1,2,4-TRIAZOLE-3-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF FROM UNIVERSAL PRECURSOR | 2015 |
|
RU2605414C1 |
URACIL DERIVATIVES WITH ANTIVIRAL ACTIVITY AGAINST SARS-COV-2 | 2021 |
|
RU2769828C1 |
METHOD OF 2-SULPHONILAMINE-1,2,4,-TRIAZOLO[1,5-a] PYRIMIDINES PRODUCTION | 2007 |
|
RU2325390C1 |
(Z)-5-SUBSTITUTED-3-(HYDROXY(ARYL)METHYLENE)-3-(PHENYLTHIO)-3,3А-DIHYDROPYRROLO[1,2-A]QUINOXALINE-1,2,4(5H)TRIONES WITH ANTIMICROBIAL ACTIVITY | 2021 |
|
RU2759006C1 |
DIAMINOTRIAZOLES, SUITABLE AS INHIBITORS OF PROTEIN KINASES | 2003 |
|
RU2350606C2 |
NEW PHOSPHORAMIDATE NUCLEOSIDE DERIVATIVES AND APPLICATION THEREOF | 2014 |
|
RU2621709C2 |
METHOD FOR PREPARING A THIO DERIVATIVE OF PYRROLIDINE-2,5-DIONE WITH A QUINAZOLINE FRAGMENT | 2021 |
|
RU2807057C2 |
Authors
Dates
2023-11-30—Published
2022-12-26—Filed