FIELD: chemistry.
SUBSTANCE: invention relates to azoloazine salts of compounds of a fluoroquinolone line of formulae 4a-c  , 5a-c
, 5a-c  , 7a-b
, 7a-b  and 8a-b
 and 8a-b  , possessing antibacterial and antiviral properties. The claimed compounds can be applied for the creation of a medication for the emergency prevention and treatment of infections, caused by pathogens of both the bacterial and viral origin, including especially dangerous ones. In general formulae 4 and 5 R=CH3, R1=C2H5; R=H, R1=C2H5; R=C2H5, R1=cyclo-C3H7, in formulae 7 and 8 R=H (7a, 8a); R=CH3 (7b, 8b).
, possessing antibacterial and antiviral properties. The claimed compounds can be applied for the creation of a medication for the emergency prevention and treatment of infections, caused by pathogens of both the bacterial and viral origin, including especially dangerous ones. In general formulae 4 and 5 R=CH3, R1=C2H5; R=H, R1=C2H5; R=C2H5, R1=cyclo-C3H7, in formulae 7 and 8 R=H (7a, 8a); R=CH3 (7b, 8b).
EFFECT: increased efficiency of the compound application.
8 tbl, 2 ex
| Title | Year | Author | Number | 
|---|---|---|---|
| 5-METHYL-6-NITRO-7-OXO-4,7-DIHYDRO-1,2,4-TRIAZOLO[1,5-ALPHA]PYRIMIDINIDE L-ARGININIUM MONOHYDRATE | 2013 | 
 | RU2529487C1 | 
| INJECTION OR INFUSION SOLUTION OF L-ARGININE SALT OF 5-METHYL-6-NITRO-1,2,4-TRIAZOLO[1,5-a] PYRIMIDIN-7-ONE MONOHYDRATE FOR THERAPY OF INFLUENZA AND OTHER VIRAL INFECTIONS | 2014 | 
 | RU2586283C1 | 
| SODIUM SALT 5-METHYL-6-NITRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINE-7-ONE DIHYDRATE | 2006 | 
 | RU2330036C1 | 
| 2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZINE-7(4H)-ONE SODIUM SALT DIHYDRATE POSSESSING ANTIVIRAL ACTIVITY | 2005 | 
 | RU2294936C1 | 
| MEDICATION POSSESSING ANTI-VIRAL ACTIVITY AND CONTAINING 2-METHYLTHIO-5-METHYL-6-NITRO-1,2,4-TRIAZOLO[1,5-a]PYRIMIDIN-7(3H)-ON | 2007 | 
 | RU2365591C2 | 
| INJECTION SOLUTION FOR TREATING VIRAL DISEASES SPECIFIED IN H1N1, H3N2, H5N1 INFLUENZA, TICK-BORNE ENCEPHALITIS AND WEST NILE FEVER | 2013 | 
 | RU2574007C2 | 
| SODIUM SALT OF 2-METHYLTHIO-6-CYANO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZIN-7(4H)-ONE, TRIHYDRATE | 2015 | 
 | RU2607628C1 | 
| 2-(4-PYRIDYL)-6-NITRO-7-OXO-4,7-DIHYDRO-1,2,4-TRIAZOLO [5,1-C][1,2,4]TRIAZINE AMMONIUM SALT SHOWING ANTIVIRAL ACTIVITY | 1987 | 
 | SU1473303A1 | 
| ETHYL ESTER OF 2-(ADAMANTAN-1-yl)-3-BROMO-7-OXO-4,7-DIHYDROPYRAZOLO[1,5-a]PYRIMIDINE-6-CARBOXYLIC ACID, HAVING ANTIVIRAL ACTION ON SARS-CoV-2 CORONAVIRUS | 2024 | 
 | RU2839407C1 | 
| METHOD FOR QUANTITATIVE DETERMINATION OF TRIAZIDE BY VOLTAMMETRY | 2019 | 
 | RU2733397C2 | 
Authors
Dates
2015-04-10—Published
2014-03-06—Filed