DIAGNOSTIC TECHNIQUE FOR CELL DYSIMMUNITY IN CHEMICAL WORKERS EXPOSED TO FORMALDEHYDE Russian patent published in 2015 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and immunology, and aims at identifying the unfavourable exposure of formaldehyde on the human body, namely on the cell immunity. The substance of the method: venous blood is sampled from the workers, measuring the formaldehyde concentration and lymphocyte count that are basic parameters of the T-cell immunity; that is followed by stating a criterion that shows the cell dysimmunity. Basic parameters of the T-cell immunity are a percentage of activated T-lymphocytes CD3⁺CD95⁺ and also a percentage of T-regulatory lymphocytes CD4⁺CD25⁺CD127^-; the criterion is an integrated index equal to CD3+CD95+ /CD4⁺CD25⁺CD127^- lymphocytes ratio. If the integrated index is 40 or more, the cell dysimmunity is diagnosed in the chemical workers exposed to formaldehyde.

EFFECT: using the invention provides the higher information value of the assessment of the xenobiotic (formaldehyde) exposure on the cell dysimmunity in the chemical workers' bodies.

2 tbl, 2 ex