INTERMITTENT DRUG FEED FROM LACHRYMAL OPENING PLUG Russian patent published in 2015 - IPC A61F9/00 A61K31/43 A61P27/02 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to ophthalmology and to devices for the intermittent active substance feed into a naso-lachrymal duct. The device comprises a tube inserted into a lachrymal opening plug cavity. The tube comprises hole, which is fluid-connected to a cavity formed in a tube body and comprising a drug. The device also comprises two or more linearly aligned dosage units for the intermittent feed inside the tube; two or more dosage units for the intermittent feed comprises a core containing the active substance, and a water-soluble encapsulating layer surrounding the core. A boundary layer between the first and second dosage unit for the intermittent feed is soluble in lachrymal fluid. A thickness and physical characteristics of the soluble boundary layer can be adjusted to control time intervals between the instants of the intermittent drug feed.

EFFECT: such implementation of the device provides the regulated intermittent feed with the controlled time intervals between the instants of the feed of one or more active substances, including in small amounts, into one or both naso-lachrymal ducts and into the lachrymal fluid through a plug in the lachrymal opening in the form of a linear sequence of feed pulses for delaying or preventing a disorder or a condition of one or more organs, namely eyes, a nose, or a throat.

16 cl, 11 dwg