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(19)

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2 539 774

(13)

(51)

IPC

C07K16/28(2006-01-01)

C12N15/12(2006-01-01)

C12N15/63(2006-01-01)

C12N5/10(2006-01-01)

A61K39/395(2006-01-01)

(21) (22)

Application

2011120194/10, 2009-10-27

(24)

Start date

2009-10-27

(22)

Actual filing date

2009-10-27

(45)

Published

2015-01-27

(72)

Inventor

Martin, Dzhoehl, Kh.Khuan, Tammi, T.Fehrkherst, Zhanett, L.Papadopulos, Nikolas, Dzh

(73)

Holder

Ridzheneron Farmas'Jutikalz, Ink.

HUMAN ANTIBODIES WITH HIGH AFFINITY TO HUMAN IL-4 RECEPTORS Russian patent published in 2015 - IPC C07K16/28 C12N15/12 C12N15/63 C12N5/10 A61K39/395

Abstract RU 2539774 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology and immunology. What is described is a recovered human antibody or its antigen-binding fragment. The antibody binds to human interleukin-4 alpha-receptor (hlL-4R). There are also described a nucleic acid molecule coding this antibody, an expression vector, a host cell, a method for producing such antibody and a therapeutic composition containing this antibody.

EFFECT: presented group of inventions can be used in medicine for treating asthma and atopic dermatitis.

15 cl, 3 tbl, 3 ex

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RU 2 539 774 C2

Authors

Martin, Dzhoehl, Kh.

Khuan, Tammi, T.

Fehrkherst, Zhanett, L.

Papadopulos, Nikolas, Dzh

Dates

2015-01-27—Published

2009-10-27—Filed