FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry. Described is an antibody, or antigen-binding fragment of an antibody, that specifically binds to human IL-4R. Also described is a nucleic acid encoding said antibody, a corresponding vector and a host cell. Also provided is a method of producing said antibody and a therapeutic composition for treating a disease associated with IL-4R, containing said antibody.
EFFECT: invention widens the range of means of treating asthma.
19 cl, 3 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| HUMAN ANTIBODIES WITH HIGH AFFINITY TO HUMAN IL-4 RECEPTORS | 2009 |
|
RU2539774C2 |
| HIGH-AFFINITY HUMAN IL-4 RECEPTOR ANTIBODIES | 2007 |
|
RU2445318C2 |
| ANTIBODIES OF HIGH AFFINITY TO IL-6-RECEPTOR OF HUMANS | 2007 |
|
RU2433138C2 |
| HUMAN ANTIBODIES WITH HIGH AFFINITY TO HUMAN NERVE GROWTH FACTOR | 2008 |
|
RU2473564C2 |
| HUMAN ANTIBODIES TO CLOSTRIDIUM DIFFICILE TOXINS | 2013 |
|
RU2628305C2 |
| HUMAN ANTIBODIES TO DELTA-LIKE HUMAN LIGAND-4 | 2007 |
|
RU2448979C2 |
| ANTIBODY TO IL-4Rα AND APPLICATION THEREOF | 2018 |
|
RU2758092C1 |
| STRUCTURES HAVING SIRP-ALPHA DOMAIN OR ITS VERSION | 2016 |
|
RU2740672C2 |
| POLYPEPTIDE LINKER FOR PRODUCTION OF MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2776302C2 |
| STABLE MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2779602C2 |
