BRIDGED SPIRO[2,4]HEPTANE DERIVATIVES AS ALX AND/OR FPRL2 RECEPTOR AGONISTS Russian patent published in 2015 - IPC C07C233/58 C07C233/60 C07C233/63 C07D211/26 C07D207/09 C07D213/40 C07D231/12 C07D233/64 C07D235/14 C07D239/30 C07D249/08 C07D277/28 C07D277/62 C07D307/52 C07D319/12 A61K31/44 A61K31/40 A61K31/426 A61K31/427 A61P11/00 A61P29/00 A61P9/00 

Abstract RU 2540274 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to bridged spiro[2.4]heptane derivatives of formula (I), wherein W means -CH2CH2- or -CH=CH-; Z means -C(O)NR3-* or -CH2NR4C(O)-*, Y means a bond or (C1-C4)alkane diyl group, R1-R4 are those as specified in the description, to preparing and using them as ALX and/or FPRL2 receptor agonists applicable for treating inflammatory and obstructive respiratory diseases.

EFFECT: preparing the compositions for treating the inflammatory and obstructive respiratory diseases.

14 cl, 1 tbl, 422 ex

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RU 2 540 274 C2

Authors

Daniel' Bur

Oliv'E Kormenbef

Sil'Vene Kren

Korinna Grisostomi

Ksav'Er Leroj

Sil'V'Ja Rishar-Bil'Dshtajn

Dates

2015-02-10Published

2010-05-17Filed