FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology. Self-assembling peptide nanoparticles (SAPN) containing T-cell epitopes and/or B-cell epitopes are described. According to the invention, the nanoparticles consist of aggregates of a continuous peptide chain comprising two oligomerisation domains bounded by a linker segment, wherein one or two oligomerisation domains contain the T-cell epitopes and/or the B-cell epitopes within their peptide sequence.
EFFECT: nanoparticles are effective as vaccines and adjuvants.
41 cl, 8 dwg, 26 tbl, 15 ex
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