NOVEL CELL-PENETRATING PEPTIDES Russian patent published in 2018 - IPC C07K14/05 C07K19/00 A61K47/42 G01N33/53 C12P21/02 A61P37/00 

Abstract RU 2670488 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to biotechnology, specifically to cell-penetrating peptides, and can be used in medicine by delivering a therapeutic cargo molecule to a mammalian cell. Peptide consists of a fragment of 15–30 amino acids of the site, extending from residue 170 to residue 220 of SEQ ID NO: 23, and contains Ser (S) at a position equivalent to position 189 of SEQ ID NO: 23.

EFFECT: invention provides efficient delivery of therapeutic peptide epitopes of a pathogen or tumour to mammalian cells.

24 cl, 2 dwg, 3 tbl, 5 ex

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RU 2 670 488 C2

Authors

Deruazi Madia

Uolker Pol

Ditrikh Per-Iv

Dates

2018-10-23Published

2013-09-12Filed