METHOD AND PHARMACEUTICAL COMPOSITIONS FOR TREATING POSTPRANDIAL HYPERGLYCEMIA ACCOMPANYING TYPE II DIABETES MELLITUS BY ADMINISTERING THROUGH ORAL MUCOSA Russian patent published in 2015 - IPC A61K9/08 A61K31/63 A61K38/00 A61K45/08 A61K47/10 A61P3/10 

Abstract RU 2543635 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: object of the invention is a method and a pharmaceutical composition in the form of a water-alcohol solution of ethanol 30-60° and water 40-70%, wherein at least one hypoglycaemic active substance is stably and completely dissolved, to be used by administering through the oral mucosa as a therapeutic agent in accurate treatment of postprandial hyperglycemia accompanying type II diabetes mellitus in a human or animal; wherein the water-alcohol solution in the composition has a volume of less than 2 ml, wherein an amount of 250mg or less of the above active substance is stably and completely dissolved, while the hypoglycaemic active substance is specified in lipophilic or amphiphilic active substances, such as gliclazide, glinides, incretins and glyphins. The invention also refers to a method for preparing this dosage form.

EFFECT: preparing the therapeutic agent for treating postprandial hyperglycemia accompanying type II diabetes mellitus.

9 cl, 20 ex

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RU 2 543 635 C2

Authors

Perovich Filipp

Mori Mark

Djumontei Zhan-P'Er

Dates

2015-03-10Published

2010-07-07Filed