FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to 1-(2-{[4-(4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}phenylcarbamoyl)butyl]methylcarbamoyl}ethyl)piperidin-4-yl ester of biphenyl-2-ylcarbamic acid or to its pharmaceutically acceptable salt. The invention also refers to a pharmaceutical composition based on the above compound, a method and an intermediate compound for producing the above compound.
EFFECT: produced is the new heterocyclic compound effective in treating pulmonary disorders, including in chronic obstructive pulmonary disease or asthma.
9 cl, 3 tbl, 170 ex
Title | Year | Author | Number |
---|---|---|---|
DIAMIDE COMPOUNDS HAVING ACTIVITY OF MUSCARINIC RECEPTOR ANTAGONIST AND ACTIVITY OF β ADRENERGIC RECEPTOR AGONIST | 2010 |
|
RU2676686C2 |
BIPHENYL DERIVATIVES | 2004 |
|
RU2330841C2 |
CRYSTALLINE FORM OF BIPHENYL COMPOUND | 2005 |
|
RU2381223C2 |
BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | 2005 |
|
RU2366656C2 |
COMPOUNDS HAVING ANTAGONISTIC ACTIVITY TOWARDS MUSCARINIC RECEPTORS AND AGONIST ACTIVITY TO BETA2-ADRENORECEPTORS | 2012 |
|
RU2606121C2 |
PYRAZOLO[1,5-a]PYRIMIDINE AND THIENO[3,2-b]PYRIMIDINE DERIVATIVES AS MODULATORS OF IRAK-4 | 2011 |
|
RU2604062C2 |
COMPOUNDS HAVING MUSCARINIC RECEPTOR AGONIST AND BETA-2-ADRENERGIC RECEPTOR AGONIST ACTIVITY | 2016 |
|
RU2709777C2 |
COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA-2-ADRENERGIC RECEPTOR AGONIST ACTIVITY | 2013 |
|
RU2661877C2 |
DERIVANTS OF BICYCLO[2, 2, 1] HEPT-7-YLAMINE AND THEIR APPLICATIONS | 2006 |
|
RU2442771C2 |
COMPOUNDS AND PHARMACEUTICAL COMPOSITION POSSESSING PROPERTY FOR GROWTH HORMONE RELEASING, METHOD FOR STIMULATION OF SECRETION OF GROWTH HORMONE FROM MAMMAL HYPOPHYSIS | 1999 |
|
RU2298547C2 |
Authors
Dates
2015-03-10—Published
2010-04-16—Filed