PEPTIDYL-DIACYLGLYCERIDES Russian patent published in 2015 - IPC C07K7/00 C07K1/04 C07K1/06 A61K38/10 A61P37/02 

Abstract RU 2545347 C2

FIELD: chemistry.

SUBSTANCE: invention relates to biotechnology, specifically to immunostimulating compounds and may be used in medicine. An immunostimulating peptide of an amino acid sequence XLYDKGYTSKEQKDCVGI, where N-terminal X is N-acetylalanine, and may be covalently linked to fatty acids, selected from C2-C25, to form PDAG (peptidyl-2,3-diacylglycerides). The resulted compound may be included in pharmaceutical formulations for stimulating an immune response.

EFFECT: invention provides efficient stimulation of an immune response in subjects and may enhance the immunogenicity of the antigenic peptide when administered with PDAG.

29 cl, 10 dwg, 9 ex

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RU 2 545 347 C2

Authors

Taker, Dzhejms D.

Dates

2015-03-27Published

2009-04-24Filed